Xadago: A New Treatment for PD Patients Experiencing “Off” Periods


A new drug has been approved for controlling Parkinson’s symptoms in people who take Levodopa but experience periods where the medication seems to not work.

“The U.S. Food and Drug Administration (FDA) has approved a new drug called Xadago (safinamide) from Newron Pharmaceuticals for people with Parkinson’s disease (PD) who are taking levodopa but experiencing “off” episodes. “Off” episodes are times when Parkinson’s symptoms, such as tremor or difficulty walking, return despite medication. They are more common as disease progresses.

Xadago is indicated as an add-on therapy for those taking levodopa/carbidopa. The safety and efficacy of Xadago were evaluated in two clinical trials that included 1,194 participants. These studies showed that, compared to people taking placebo, those on Xadago experienced more beneficial “on” time (when PD symptoms are reduced) and less “off” time (when PD symptoms are increased).”

To read more about this new treatment option, read on at the link below and talk to your neurologist: