Cardiorespiratory exercice and motor skill learning

Title of the study : The effect of cardiorespiratory exercice on motor skill learning in Parkinson’s disease

Principal Investigator : Julien Doyon, PhD

Co-investigator: Louis Bherer, PhD

Site address: IUGM 4545 chemin Queen-mary, Montréal, Qc, H3W 1W4

Background : Parkinson’s diseaseB (PD)is the second most common neurodegenerative disorder after Alzheimer’s disease which affects not only the functional capacity but also compromises the quality of life. More recently, studies have been conducted to explore the effects of physical activity , and a cardiorespiratory exercise, in particular, in PD. In recent years, a few investigators have examined the effects of music, with preferred musical rythms in particular, to alleviate motor deficits in PD patients. However, the mechanisms for this clinical effect remain largely unknown.

Purpose of the study : The main aim of the present study is to investigate the effects of cardiorespiratory exercise with or without preferred musical rhythms in PD Patients on motor sequence learning. More specifically,the research team  will try, through Neuroimaging techniques and network analyses approaches, to identify the neural mechanisms responsible for those exercise‐dependent changes. Secondary outcomes will include motor functional capacities, and quality of Life.