Ongoing projects
AXIS 1: CLINICAL AND TREATMENT RESEARCH
A Global Study to Assess the Drug Dynamics, Efficacy, and Safety of GZ/SAR402671 in Parkinson’s Disease Patients Carrying a Glucocerebrosidase (GBA) Gene Mutation – Sanofi / Genzyme
Assessment of Efficacy, Safety, Tolerability, and Pharmacokinetics of ABBV-8E12 in Progressive Supranuclear Palsy - Postuma, MD, PhD – McGill – Corporation abbVie
Behavioral and neuroimaging biomarkers of Parkinson’s Disease: Neuroimaging stream - Doyon, PhD – UdeM and McGill
Behavioral and neuroimaging biomarkers of Parkinson’s Disease: Behavioral stream – Doyon, PhD – UdeM and McGill
Validation of a mobile app for the detection of tremors and bradykinesia – Duval, PhD – UdeM et UQAM
Exploratory study for the validation of magnetic resonance imaging bionarkers for Parkinson’s disease – Soucy, MD, PhD – Concordia, UdeM et CHUS
Study on the effect of Mirtazapine on depression in patients diagnosed with Parkinson’s disease - Panisset, MD, PhD – UdeM and CHUM
Effect of long-acting levodopa on obstructive sleep apnea in Parkinson’s disease – Kaminska, MD, MSc – McGill University
National Parkinson Foundation Patient Registry – Lafontaine, MD, MSC – McGill University / National Parkinson Foundation
Imaging brain structures involved in human walking with Parkinson’s disease (PD) – Paquette, PhD, Dr Soucy, MD – McGill University
Impact of an exercise program on proprioceptive performance in Parkinson’s disease – Messier, PhD, Blanchet, Md, PhD – University of Montreal
A novel exercise modality to improve motor learning in PD - Roig, PhD – McGill University
AXIS 2: NON-MOTOR SYMPTOMS
Understanding resilience and disease by using language and the brain to predict individual outcomes – Klein, PhD – McGill University
Identification of a specific olfactory disease profile in Parkinson’s disease – Frasnelli, PhD – Université du Québec à Trois-Rivières
Auditory dysfunction associated with Parkinson’s disease: a pilot study characterizing the peripheral and central auditory signs in Parkinson’s disease - Fuente, PhD – UdeM
Role of dopamine in prioritizing memory content: Implications for Parkinson’s disease – Sharp, MD, MSc – McGill
The Physical and Cognitive Benefits of Dance Movement Therapy for People with Parkinson’s Disease – Gold, MD, PhD – McGill and Concordia University
Quantitative Motor Control for Decision-Making – QTMODEM – Messier, PhD – UdeM
MRI and Virtual Navigational Strategies in Parkinson’s Disease – Bohbot, PhD – McGill University, University of Montreal
Role of brain cholinergic degenerations in the Mild Cognitive Impairment of Parkinson’s disease: A PET study with the 18F-Fluoroethoxybenzovesamicol (FEOBV) – Bédard, PhD – UQAM, UdeM, McGill University
The effects of eye-movement training on cognitive performance – Khan, PhD – University of Montréal
Percpetual-Cognitive Training in PD - Faubert, PhD – University of Montreal
Electrical Brain Stitmulation and Impulsive Control Disorders
AXIS 3: MOLECULAR AND CELLULAR BIOLOGY
Open Science Clinical Biological Imaging and Genetic Repository – C-BIG Repository
Targeted Next-Generation Sequencing and Genome-Wide Association Study of Parkinson’s disease patients in Quebec
Epidemiological and genetic study of Parkinson’s disease in Quebec
Clinical – genetic study of GBA mutations in Parkinson’s disease and REM sleep Behavior Disorder
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Completed Project
AXIS 1: CLINICAL AND TREATMENT RESEARCH
Home and community mobility in elderly healthy individuals ans patients with Parkinson’s disease
The impact of drug-induced dyskinesia and its management on daily-life activities
Assessment of gait sensors for Parkinson’s disease – Mc Laren, PhD – Concordia University
Comparison of the efficiency of levodopa and dopamine agonists on the mobility in the community and the physical activity level of people with Parkinson’s disease
Treatment of sleep apnea in Parkinson’s disease
Detection and automatic follow-up of the motor symptoms in patients with Parkinson’s disease
Caffeine as a Therapeutic Agent in Parkinson’s disease
Association of Cognitive dysfunction with Orthostatic Hypotension in patients with Parkinson’s disease
Validation of the Movement Disorders Society PD diagnostic criteria
The effect of cardiorespiratory exercice on motor skill learning in Parkinson’s disease
Freezing mechanisms in Parkinson’s disease
AXIS 2: NON-MOTOR SYMPTOMS
Smoking and Cognition in Parkinson’s disease
Cognitive effect of transcranial magnetic stimulation on patients with Parkinson’s disease and mild cognitive impairment
Cognitive Reserve and Parkinson Disease : Can an extra Language help in more ways than one ?
Studying the resting-state networks associated with cognitive deficits in Parkinson’s disease (PD)
AXIS 3: MOLECULAR AND CELLULAR BIOLOGY
Genome wide association study of Parkinson’s disease and REM sleep Behavior Disorder
Targeted next generation sequencing of 58 Parkinson’s disease- related genes
The role of SMPD1 in Parkinson’s disease
Association study of the melanoma gene MC1R and Parkinson’s disease
The interplay between nicotinic receptor and nicotine metabolism genes, smoking and Parkinson’s disease
DNAJC13 in Parkinson’s disease
Study of novel familial genes in Parkinson’s disease
Replication study of essential tremor genetic loci in Parkinson’s disease
Study of HIP1R, LRRK2 and SNCA in Parkinson’s disease